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KMID : 1240020210250000003
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International Neurourology Journal
2021 Volume.25 No. 0 p.3 ~ p.7
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Irreversible Bladder Remodeling Induced by Fibrosis
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Kim Su-Jin
Kim Ja-Young
Na Yong-Gil
Kim Khae-Hawn
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Abstract
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Underactive bladder and impaired bladder compliance are irreversible problems associated with bladder fibrosis. Remodeling of the extracellular matrix is regarded as an important mechanism associated with bladder fibrosis. However, various risk factors and conditions contribute to the functional impairment of the bladder associated with fibrosis, and there is limited knowledge about bladder fibrosis-associated problems in the field of neurourology. Further studies are thus necessary to elucidate the underlying mechanism of bladder fibrosis and to identify effective treatment.
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KEYWORD
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Urinary bladder, Fibrosis, Extracellular matrix, Lower urinary tract symptoms, Collagen
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